The Gut-Brain Axis and the Psychobiome

The gut-brain axis, a bidirectional communication between gut microbiota and the central nervous system (CNS), may play a role in cognitive function, digestion, and mood. Studies show that 80-90% of the fibers in the vagus nerve are linked to the gut, providing a physical link through which the gut microbiota communicate with the brain. Relatedly, the term psychobiome is used to describe the interaction between a person’s collective microbiome and his mental state. A diverse and balanced microbiome can help maintain the gut-brain axis. A psychobiotic is used to describe the commensal bacteria that play a role in the gut-brain axis and support brain health. For a comprehensive review of the Gut Brain Axis it’s worth checking out the research paper “The Gut–Brain Axis and the Microbiome: Mechanisms and Clinical Implications”

Bifidobacterium longum 1714™: A Trail-blazing Psychobiotic

1714™, a unique strain of Bifidobacterium longum, is an up-and-coming psychobiotic that can help support the management of occasional stress and its biochemical expression within the human body. This psychobiotic exerts its effect by supporting NF-kB signaling and cytokine production, supporting IL-10 levels, and targeting the HPA axis to support healthy cortisol levels. 1714™ may support mental health, cognitive process, neurotransmitters, and overall feeling of well-being.

In a 4-week human trial, 1714™ reduced perceived stress, improved memory performance, reduced mental fatigue, positively supported brainwave activity, and improved ability to handle occasional stress.

Zen Biome Key Ingredients

L-Theanine

L-theanine, found in high concentrations in green tea, helps support neurotransmitters. L-theanine can help support serotonin, GABA, and dopamine levels. It can also produce a calming effect while simultaneously supporting alpha brain waves.

LEMON BALM EXTRACT

This perennial herb in the mint family may increase feelings of drowsiness and has mild sedative properties to help with occasional inability to fall asleep. Lemon balm can also help calm occasional nervousness and excitability, supporting mood.

BIFIDOBACTERIUM LONGUM (1714™)

A high-potency psychobiotic, 1714™ helps support the body’s response to occasional stress, and the body’s neurocognitive processes. This strain helps support the HPA axis and cortisol levels. In studies, it also helped support memory performance and an improved perception of stress.

Ages 8+: Take 1 capsule in the evening with or without a meal, or as directed by your healthcare practitioner.

Children under 8 years of age, please consult with your healthcare practitioner. CAUTION: If you are pregnant or nursing; taking any medication; have a medical condition, consult your doctor before using this product. Keep out of reach of children. Do not use if safety seal is broken or missing.

*THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION or TGA. THESE PRODUCTS ARE NOT INTENDED TO DIAGNOSE, TREAT, CURE OR PREVENT ANY DISEASE.

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https://pubmed.ncbi.nlm.nih.gov/25794930/

https://www.nature.com/articles/tp2016191

https://pubmed.ncbi.nlm.nih.gov/25251188/